WHO WE ARE

For over two decades the Issa Lab has studied the function of specific genes that encode epigenetic regulators. Utilizing our proprietary screening tools we are able to determine and validate a compounds’ potential epigenetic activity. We study small molecules in cellular and animal models of disease to identify and validate potential epigenetic targets. We have identified a new molecule that targets the epigenetic activity of CDK9, leading to cancer cell inhibition and sensitivity to chemotherapy and immunotherapy.